Drug delivery systems enable and enhance the clinical utility of drug molecules by increasing their localization to disease areas while reducing their exposure to healthy tissues. The outcome is safer and more effective therapeutics that improve human health. Our drug delivery platform uncovers and maximizes the therapeutic potential of many diverse drug molecules.

Lipid nanoparticles (LNPs) are carefully designed drug delivery technologies that can target drugs to their sites of action, and release drugs in a controlled manner.

Despite progress in drug discovery, many compounds have undesirable physiochemical or pharmacokinetic properties, or are unable to reach their intracellular destination due to their inability to cross cell membranes.

INT’s patented ScaffoLD® lipid technology can reliably encapsulate various drug modalities (small molecule, RNA/DNA, peptide) in our LNP system. The LNP is then specifically engineered to accumulate in sites of inflammation or cancer, enter disease cells efficiently, and release the encapsulated drug(s) inside the cells.  As a result, the drug(s) are made safer and more effective.

Our Multi-Cargo LNP system can co-load different drug modalities into the same nanoparticle to ensure optimal pharmacokinetics and bio-distribution in combination therapies.